is Ziagen used for?
is used to treat HIV-1 infection in combination with other antiretroviral
medications. Ziagen is only
proven to work when taken in combination with other antiretroviral
medications. Ziagen belongs to
the class of drugs known as nucleoside reverse transcriptase inhibitors.
Warnings Concerning Ziagen:
you experience signs or symptoms of a hypersensitivity reaction (severe
allergic reaction) at any time while you are taking Ziagen, you must stop
taking Ziagen and contact your health care provider immediately. If
you have a skin rash or two or more of the following symptoms you may be
having a hypersensitivity reaction:
- nausea, vomiting, diarrhea, or stomach pain
- severe tiredness, achiness, or a general ill feeling
- sore throat, cough, or shortness of
you experience a hypersensitivity reaction, at any time while taking
Ziagen you must never take Ziagen again. If
you take Ziagen again, more severe symptoms will reappear within hours,
which may include life-threatening low blood pressure and death.
medication guide for patients comes with every Ziagen prescription. Read
the medication guide carefully. In
addition, your pharmacist will give you a warning card listing the
symptoms of a Ziagen allergy. Carry
this card with you.
can cause a condition called lactic acidosis (accumulation of lactic acid
in the body) together with an enlarged liver, which can be a serious and
you have a history of liver problems, your health care provider will
evaluate and decide if Ziagen is right for you.
Precautions with Ziagen:
- Because resistance to the HIV virus can occur quickly with
single-drug treatment, Ziagen should always be taken in combination
with other antiretroviral medications. Ziagen
should not be taken alone to treat HIV. If
your current treatment is failing, Ziagen should not be added as a
- Ziagen is not a cure for HIV infection. At
present, there are no results from studies evaluating long term
suppression of HIV or disease progression. You
may continue to experience illnesses associated with HIV infection,
including opportunistic infections.
- You should remain under the care of a physician when using Ziagen. If
you stopped taking Ziagen for reasons other than a severe allergic
reaction, it is possible to begin taking Ziagen again with continued
monitoring by your doctor for such a reaction.
- Ziagen has not been shown to reduce the risk of transmission to
others through sexual contact or blood contamination.
should I tell my doctor or health care provider?
your doctor or health care provider if you are:
- trying to become pregnant or are pregnant.
- breast-feeding or thinking about breast-feeding while taking Ziagen.
are some possible side effects of Ziagen? (This is not a complete list of side effects reported with
Ziagen. Your health care provider can discuss with you a more complete
list of side effects.)
the warning card of Ziagen allergy symptoms with you. Tell
your health care provider immediately about any side effects you
experience while taking Ziagen. Serious
and life threatening allergic reactions have been associated with Ziagen
(See "Special Warnings").
in body fat have been seen in some patients taking antiretroviral therapy.
These changes may include increased amount of fat in the upper back
and neck (?buffalo hump?), breast, and around the main body.
Loss of fat from the legs, arms, and face may also happen.
side effects of Ziagen include:
- feeling tired
- loss of appetite
- trouble sleeping
- joint pain
- shortness of breath
more detailed information about Ziagen, ask your health care provider.